Scientists announced: New genes affecting muscle loss found

Scientists discovered new genes that trigger muscle loss. Studies in Sweden and England shed light on treatment methods for sarcopenia, especially in older individuals. Gene data analyzed using artificial intelligence revealed that the USP54 gene plays an important role in muscle weakening. These findings may help develop exercise-based interventions to preserve muscle mass in the elderly.

Scientists identify new genes that play key roles in the process of muscle loss. A joint study by the Karolinska Institutet and Karolinska University Hospital in Sweden and Anglia Ruskin University in England provides new information about the genes that trigger muscle loss. Researchers announced that they have new findings that may impact treatments related to this process for older people with sarcopenia.
Physical exercise stands out as the only recommended treatment method to prevent muscle weakening and sarcopenia. In the study, gene expression data of individuals between the ages of 21-43 and 63-79 were analyzed. Using artificial intelligence, the top 200 genes that interact with aging and exercise were identified. In particular, the USP54 gene was found to play a critical role in muscle weakening and loss in older individuals.
Dr. Lívia Santos from Nottingham Trent University stated that they wanted to identify genes that will delay the effects of the aging process and said, “Muscle loss is a big problem. This increases the risk of falls and the likelihood of developing physical disabilities. “Understanding the mechanisms that regulate muscle weakening is an urgent need,” he said.
Researcher Dr. Janelle Tarum, on the other hand, drew attention to the potential of artificial intelligence in sarcopenia research and stated that discovering new genes will contribute to studies in this field.
The results of the research are considered an important step that can help develop more conscious exercise interventions for preserving muscle mass in older individuals.
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